MP Journal of Medical Research
Presented at 13ème Congrès Somipev-Zerouali, Marrakech, 5–7 December 2025 · All posters from this congress
OncologyOpen accessPoster communication · 2026-0037

Measles in Pediatric Oncology

English version of a poster presented in French.

Fatima Ezzahrae Kouzi1✉, K. Elmkaddem1, S. Bouramdane1, S. Benmiloud1

  1. 1 Service d’Hémato-oncologie pédiatrique, CHU Hassan II Fès

Received 15 October 2026 · Accepted 15 October 2026 · Published 15 October 2026

Article PDF · Original poster (PDF)

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Key messages

  1. La rougeole est particulièrement sévère chez l'enfant immunodéprimé traité pour un cancer.
  2. Une prise en charge précoce et coordonnée améliore l'évolution clinique et permet la reprise de la chimiothérapie.
  3. La prévention et le dépistage sont essentiels pour réduire la morbidité et la mortalité liées à la rougeole en oncologie pédiatrique.

Abstract

Introduction

Measles is a highly contagious viral infection transmitted via airborne route, which can be particularly severe in immunocompromised children, especially those treated for cancer, with increased risk of systemic complications.

Materials and methods

This is a retrospective descriptive study of four patients with acute lymphoblastic leukemia followed in pediatric hemato-oncology who developed measles during treatment. Clinical, biological, and evolutionary data were extracted from medical records.

Results

All four patients had leukopenia and severe neutropenia. Three had favorable outcomes with rapid rash resolution and progressive chemotherapy resumption. One patient developed severe post-measles pneumonia requiring intensive care and died. Management included isolation, vitamin A, hydration, antipyretics, ENT and skin care, and temporary chemotherapy interruption.

Conclusion

Measles in children with cancer remains a high-risk infection. Early diagnosis and adapted management allow favorable outcomes. Gradual chemotherapy resumption is possible after recovery. Prevention through post-exposure prophylaxis and hygiene measures is essential in pediatric oncology.

Original poster

References

  1. Moss WJ. Measles. Lancet. 2017 Jan;390(10111):2490–2502.
  2. Rosen JB et al. Measles transmission in immunocompromised children.
  3. Clin Infect Dis. 2019;68(5):850–857.
  4. Bellini W et al. Centers for Disease Control and Prevention.
  5. Epidemiology of measles in the immunocompromised. MMWR. 2015.
  6. WHO. Measles Fact Sheet. World Health Organization, 2019 & 2021 updates.
  7. Pui CH, Yang JJ, Hunger SP et al. Childhood acute lymphoblastic leukemia: progress through collaboration. J Clin Oncol. 2021;39(19):2189–2203.
Keywords
measles · pediatric oncology · acute lymphoblastic leukemia · immunosuppression · infectious complications
Received
15 October 2026
Accepted
15 October 2026
Published
15 October 2026
Peer review
Single-anonymized review by the Editorial Board · How we review
License
© The Authors 2026. Distributed under CC BY 4.0
Journal
MP Journal of Medical Research · ISSN 3144-8402

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